Z702455
Sigma
Chirality in Drug Design and Development
| ISBN-10: | 0-82475062-4 |
| ISBN-13: | 978-0-82475062-6 |
Description
| General description | Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals -- supporting researchers as they critically evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds. |
Properties
| publication info | I. Reddy and R. Mezvar, ed., Marcel Dekker, 2004, 444 pp., hard cover |
Table Of Contents
| Table of Contents | Effects of Crystal Structure and Physical Properties on the Release of Chiral Drugs Use of Chiral Excipients in Formulations Containing Chiral Drugs Transport of Chiral Molecules Across the Skin Stereoselective Drug Delivery through Prodrug Approach Stereoselectivity in Drug Action and Disposition: An Overview Stereoselectivity in Pharmacokinetics and Pharmacodynamics: Selected Classes of Drugs Stereospecific Pharmacokinetics and Pharmacodynamics: Cardiovascular Drugs Chiral Inversion Bioequivalency Determination of Racemic Drug Formulations: Is Stereospecific Assay Essential? Regulatory Considerations in Drug Development of Stereoisomers |
